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Best Cardiovascular Support -
60 Vcaps, (Doctor's Best)
- Science-Based Nutrition
- Featuring Flavoxine
- Helps Maintain Cholesterol Levels Already in the Normal Range
- Enhances Cardiovascular Function
- Dietary Supplement
Flavoxine is a new, all natural patented proprietary combination of extracts from Citrus and Phellodendron amurense. Animal studies have shown that the ingredients in Flavoxine possess beneficial effects on heart function and support the maintenance of healthy levels of cholesterol. Supplementation with Flavoxine in a double-blind, placebo-controlled human clinical trial also resulted in significant benefits to cardiovascular health and cholesterol maintenance.- Helps Maintain Cholesterol Levels Already in the Normal Range
- Promotes Healthy Heart Function
RESEARCH DATA
Helps promote healthy heart function and maintain cholesterol levels that are already in the normal range.
Maintaining healthy heart function is best accomplished by a multi-disciplinary lifestyle approach, including tactics such as healthy eating habits, a regular exercise routine, stress reduction techniques, keeping body weight in the healthy range, maintaining healthy cholesterol levels, and regular check-ups with a physician. Additionally, supplementing the diet with nutraceuticals that promote healthy heart function can be very beneficial.
Doctor’s Best is pleased to now carry the supplement Best Cardiovascular Support featuring Flavoxine to help its customers promote healthy heart function, and maintain their already normal cholesterol within a healthy range. Flavoxine is a combination of two different extracts; one from Phellodendron amurense tree bark, and one from orange peel standardized to polymethoxyflavones (PMFs).
Phellodendron amurense, also known as the Amur Cork-Tree, is native to northern and northeastern China, Siberia and Japan. One of the major constituents of Phellodendron amurense bark are isoquinoline alkaloids such as berberine, which give the bark its bitter taste. The bark generally contains between 0.6-2.5% of berberine, and the alkaloid content increases as the tree ages. Some of the other constituents that have been found in the bark include small amounts of palmatine, magnoflorine, phellodentrine, jatrorrhizine, candicine, and meispermine.
Berberine has been found to have significant supportive effects on serum lipid parameters in hamsters as well as in humans. In addition to studies suggesting a supportive role for helping to maintain cholesterol levels already within the normal range, both animal and human studies suggest berberine may have a number of other positive effects that help the heart stay healthy. These include supporting both clinical and physiological measurements of heart function, improving quality of life and modulating catecholamine levels under certain circumstances. It also appears to be well tolerated in humans, with no major side effects seen in a recent human study involving 156 subjects. There was only a trend toward increased mild digestive symptoms in the treatment group versus the control. A human study that monitored the ratio of berberine levels in the plasma as compared to effectiveness in supporting heart function after two weeks of consuming a 1.2 gram per day oral dose found that those individuals with higher blood berberine levels had more positive and beneficial cardiovascular effects.
Polymethoxylated flavones, or PMFs, are present in citrus fruits. Several common PMFs include tangeretin and nobiletin, which are found in orange, tangerine, and sour orange peels. In a study on hamsters, effects of three different combinations of citrus derived PMFs were compared, including a 97.4% pure tangeretin extract, an extract mixture of 63% tangeretin, 26% nobiletin, and 4% other minor PMFs, and a commercial extract containing 22% nobiletin, 16% sinensetin, 2.4% tangeretin, and 7.7% unidentified PMFs from tangerines. All three different PMF extracts were shown to have similar supportive effects on parameters of cholesterol health in the hamsters.9 Animal studies also demonstrated the bioavailability of certain PMFs by detecting metabolites in the serum, liver and urine. Some PMF metabolites have been shown to accumulate in certain tissues including the liver, suggesting localized availability to confer their beneficial effects.
Most importantly, a preliminary unpublished double-blind placebo controlled study on Flavoxine has recently been completed. A total of 45 subjects completed the study. Both normal and overweight human subjects were given either Flavoxine or placebo with food in both the mornings and evenings for a total of eight weeks.1 In this study Flavoxine showed statistically significant supportive benefits on several parameters of heart and cholesterol health, in both overweight and normal weight participants. In addition, although all of the study groups lost weight, both groups that were administered Flavoxine lost significantly more weight than the placebo groups. Flavoxine was well tolerated in the study.
Studies on the individual components as well as the preliminary clinical trial on the combination product itself suggest that in conjunction with healthy lifestyle choices, Best Cardiovascular Support featuring Flavoxine may be an important additional supplement to help support cholesterol levels already in the normal range and overall healthy functioning of the heart.
SUGGESTED USAGE
Take one capsule twice daily with food.
Warning: Do not take if pregnant or lactating, or taking any prescription medication or receiving medical treatment without consulting your physician. Keep out of the reach of children.
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Retail Price: $39.99
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Best Cardiovascular Support -
60 Vcaps, (Doctor's Best)
Flavoxine 600 mg
(a proprietary blend of patended extract from Citrus and a proprietary extract from Phellodendron amurense).
Other Ingredients: Modified cellulose (vegetarian capsule), dicalcium phosphate, silicon dioxide.
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Best Cardiovascular Support -
60 Vcaps, (Doctor's Best)
Editor's rating: 8.2 out of 10
User's rating:  0%  0%
USER'S OPINION
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Best Cardiovascular Support -
60 Vcaps, (Doctor's Best)
GUARANTEE/ SHIPPING INFORMATION
Best Cardiovascular Support - is shipped in a discrete, unmarked package. Orders are processed immediately and usually take about 3 to 5 working days to be received. We do ask that you try it for 2 to 3 weeks to feel the full effects. Any information received is used only for order processing and shipping purposes. Your information, such as e-mail address, will never be disclosed to a third party.
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Best Cardiovascular Support -
60 Vcaps, (Doctor's Best)
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Best Cardiovascular Support -
60 Vcaps, (Doctor's Best)
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